Showcasing Advances in Multiple Myeloma Research at the 75th HSBMB Conference

Researchers from partners NKUA and NHRF actively participated in the 75th National Conference of the Hellenic Society of Biochemistry and Molecular Biology (HSBMB), presenting innovative research that advances our understanding of multiple myeloma and its progression.

During the conference, Elisavet Deligianni presented her poster titled "Unraveling Interactions between the DNA Damage Response Network and the Immune System in Multiple Myeloma." Her work explores the complex relationship between DNA repair pathways and immune system responses in multiple myeloma, aiming to reveal novel mechanisms that could inform future therapeutic approaches. The presentation sparked engaging discussions and valuable exchanges with fellow researchers in the field.

Panagiotis Malamos presented his poster titled "DNA Damage Response and redox status reveal determinants of treatment sensitivity in multiple myeloma cells", from research conducted as part of his PhD thesis, focusing on how DNA damage, DNA repair mechanisms, redox regulation, and chromatin structure collectively influence treatment sensitivity in multiple myeloma cells. The work contributes to a deeper understanding of the molecular determinants of therapy response and highlights potential avenues for improving patient outcomes.

The conference also featured a presentation by Paraskevi Karousi, who addressed one of the key challenges in plasma cell disorders: predicting the progression of Monoclonal Gammopathy of Undetermined Significance (MGUS) to multiple myeloma. Her research investigates the integration of proteomics, flow cytometry, and artificial intelligence to maximize the information obtained from CD138+ cells isolated from bone marrow biopsies, offering promising perspectives for earlier and more accurate risk assessment.